No single method of drug administration is ideal for all drugs in all circumstances. There is a misconception that there is a placental barrier providing protection to the fetus. The food and drug administration, or fda, tests foods, cosmetics, and drugs to prevent the sale of. In recent years, seven rights the five rights plus right response and documentation. Phrd 4002 principles of drug action i fall 2018 syllabus page 3 evaluation will largely be based on assessing your understanding of concepts and principles, and your ability to apply this understanding in intelligent and reasonable ways, including higherorder abilities. The different types of drugs formulations and their respective advantages and disadvantages. Drug and patientrelated factors determine the selection of routes for drug administration. The rcn website provides information and resources to support nurses and other health care practitioners in their medicines management.
Describe the physicochemical and physiological factors that influence the absorption of drugs from enteral and parenteral routes of administration, their distribution within the body, and their routes and mechanisms of elimination. Principles of pharmacokinetics learning objectives. Principles of medication administration free download as word doc. Administration of controlled drugs drugs should be administered in line with relevant legislation and local standard operating procedures. Summary of principles of drug administration youtube. In actual fact, public administration equals as an activity or process mainly concerned with the means for carrying out prescribed ends while waldo 1968 opines that 296 298 fundamentals of politics and governance principles of public administration 299 administration is a type of cooperative human effort that sector. The medication practice standard describes nurses accountabilities when engaging in medication practices, such as administration, dispensing, medication storage, inventory management and disposal. This guidance represents the food and drug administration s fdas current thinking on this topic. Scribd is the worlds largest social reading and publishing site. Principles of drug administration dose biochemistry.
Administration, labelling and general principles of drug. Primary goals of clinical pharmacokinetics include enhancing ef. The purpose of this guideline is to establish principles in the administration of medication. The article also presents recent advances in otic drug deliveries as well as potential limitations. Responses to drug administration 2 of 5 tolerancedecreased response to the same amount. Principles of medication administration intravenous therapy. Safe medication principles quiz i page 1 safe medications principles 1.
If a drug substance has application in an emergency in which the patient may be comatose or unable to take oral medication, an injectable form of the medication may also be prepared. Skin topical dermal oil or ointment for local action antiseptic cream and lotion sunscreen lotion and powders 27. The right medication when administering medications, the nurse compares the label of the medication container with medication form. Safe governance principles apply to all health and social care settings and individual practices where controlled drugs are prescribed, supplied, stored, administered or transported. Drug drug or food drug interactions that affect the metabolism and excretion of drug in the body. January 11, 2002 this document supersedes the draft document, general principles of software validation, version 1. Aerosols localtopical route of drug administration in this route the drug is applied on the skin. Safe medication principles quiz 2 page 1 safe medications principles 1. Prescriptions should include the full names of drugs, both brandname and generic. If a patient says that this is not the medication they are supposed to receive, reassure. Jun 18, 2016 drugs on schedules 3, 4 and 5 are not kept in a controlled drug cupboard, but are locked away, with the exception of temazepam a schedule 3 drug. Condition of the patient unconscious, vomiting, diarrhoea. The production of this text has raised many questions concerning the data available relating to this method of medication administration. Principles of drug administration free download as word doc.
In the united states, drugs were not regulated until passage of the pure food and drug act in 1906. Principles of medication administration intravenous. Unauthorized drug errorc, administration of medication not authorized by a legitimate. Principles for pharmacybased medication administration services.
Claytons basic pharmacology for nurses, 18th edition multiple choice. Nurses have traditionally followed the five rights of medication administration patient, drug. Guidelines for drug administration kee, hayes, and mccuistion. Bds medication administration curriculum section iv 2011. Principles and modes of drug administration request pdf. It absorbs in the mouth so that its absorption drug stability. Section iv when you are finished with this section, you.
The basic principles that you will always follow are. Describe the principles of medication administration p 2. Noting the patients age and, when appropriate, weight d. Many other examples of therapeutic situations affecting dosage form design.
Principles for pharmacybased medication administration. This method produces a more rapid response than oral or rectal routes and also bypasses the sometimes. Chapter 20 principles of drug administration injection technique chapter contents learning outcomes 158 indications 158 safety considerations 159 intramuscular injection i. Basic principles of drug action and drug interactions willihnganz. Principles of drug administration to provide safe drug administration, the nurse should practice the rights of drug administration. Safe and accurate medication administration is an important and potentially. Pharmacokinetic and pharmacodynamic principles of illicit drug use and treatment of illicit drug users. Introduction drug administration is very important and can be a dangerous duty given correctly restore patient to health given incorrectly patients condition can worsen medical assistant must understand principles of pharmacology understand fundamentals of drug administration routes dosage calculations.
Rapid onset of action due to rapid access to circulation. Principles and methods of drug administration author. Discuss the influences of the patients age on the effects of. Principles of medication administration when you give medications, regardless of the type of medication, there are some basic principles that you will always follow. Do not crush or mix medications into other substances before. Assess clients ability to swallow before administering p. Most of the drugs can be administered by different routes.
Choice of medication formulation alimemazine trimeprazine tartrate25 7. Principles of business administration build students competency levels use as classroom practice tests 100 questions and answers prepare students for competition. Guide to good nursing practice administration of medication. If one of nursings primary roles is the safe administration of medications, it is important to. General principles of pharmacokinetics and pharmacodynamics. However, quality in medication administration is not simply a matter of adhering to these five rights cox, 2000. Same as oral drug can be administered for local effect ensures greater potency because drug directly enters the blood and. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets. Final guidance for industry and fda staff document issued on. Nov 17, 2019 while there are several principles of drug administration, the five important ones are. Finally, the potential for an extended duration of effect is a key consideration when choosing drug formulations. Relative measure of the toxicity or safety of a drug. Principles of drug administration drug therapy in special populations objectives upon completion of this lecture, student will be able to 1.
The drug administration phase identifies drug dosage forms and routes of administration. Unfortunately, patients are frequently harmed or injured by medication errors. Mas encompasses pharmacist administration of medications, supporting patient self administration, and all related. Discuss the different routes of drug administration 3. Principles and modes of drug administration springerlink. Principles of medication administration principles include 3 checks and 10 rights.
Apply the basic principles of interpretation of serum drug. A library and resource enter on alcohol, tobacco, other drugs, mental health and wellness 1. Health and safety and clinical risk management 47 9. Drug administration drugs msd manual consumer version. In this administration the drug is administered in the gaseous form. The primary focuses are on the various administration routes and their formulation principles. Place drug directly into a medicine cup or on a clean paper towel. Request pdf principles and modes of drug administration it becomes more than essential for a clinical pharmacologist to understand the various principles. The medication should not be chewed, swallowed, or placed under the tongue e. Sep 06, 2014 the abused drug, cocaine, is generally taken by intranasal sniffing. Renal diseases which affect glomerular blood flow and filtration, tubular secretion, reabsorption and renal parenchymal mass alter drug clearances and lead to the need for alterations in dosage regimens to optimise therapeutic outcome and minimise the risk of toxicity. Talk with the individual and explain what you are doing before you give medications. Department of health and human services food and drug administration. Factors associated with errors were drug characteristics administration route, complexity of preparation, drug class.
Take a quick interactive quiz on the concepts in principles of medication administration or print the worksheet to practice offline. The ten rs of safe multidisciplinary drug administration guildhe. Before removing the container from the drawer or shelf b. Study of biochemical and physical aspects of drug effects absorption. The various factors that affect drug absorption, drug distribution and drug excretion. The various factors that affect drug absorption, drug distribution and drug. The various routes of drug administration and their respective advantages and disadvantages for specific therapeutic indications. This includes the administration of medicines, a joint publication between the rcn and rps. Section iv when you are finished with this section, you will. Department of geriatric medicine, university of glasgow. Pharmacokinetics relationship of drug concentration in plasma or at site of action and time after drug administration net effect of absorption distribution elimination. Common parenteral routes of drug administration include. This phase describes the method by which a drug dose is made.
Apply the basic principles of interpretation of serum drug concentrations in practice. The central goal of nursing pharmacology is to enable nurses to provide medications to patients safely and appropriately using the route best suited for the. Principles for codevelopment of an in vitro companion. Mar 22, 2015 measurement of the relationship between drug concentration and therapeutic or toxic response in a large number of patients allows development of a therapeutic range or target concentration for that drug figure 1692.
Guidance for industry food and drug administration. Medication safety principles and practices pharmacotherapy. Phrd 4002 principles of drug action i fall 2018 syllabus page 2 of 12 iv curricular outcomes educational outcomes cape 20 document 1. Because the oral route is the most convenient and usually the safest.
While there are several principles of drug administration, the five important ones are. Prescription errors can be minimized by observing all of the following practices, except for. To save time, nurses should prepare injectable medications in several syringes at a time, and then label them. For example, depot injection of certain drugs, such as contraceptives, can provide an extended effect with a single injection. Principles of drug administration dose biochemistry chemistry. Nov 22, 2012 normal renal function is important for the excretion and metabolism of many drugs. Principles of business administration 20 exam international career development conference, 20 this comprehensive exam was developed by mbaresearch and curriculum center, under contract with deca, inc. Principles of drug administration in renal insufficiency. Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient. Principles for pharmacybased medication administration services pharmacists and members of the pharmacy team have important roles and responsibilities in the provision of pharmacybased medication administration services mas.
Developed october, 2019, expires october, 2021 provider. These practice questions will help you master the material and. A nurse should check the medication package three times before giving the drug, and once more before she tosses the packaging into the trash can. Modes or routes of drug administration vary from the widely followed oral route to parenteral and inhalational routes. If the medication is intended for systemic use and oral administration is desired, tablets andor capsules are usually prepared because they are easily handled by the patient and are most convenient. Three principles outline the expectations related to medication practices that promote public protection. A route of administration in pharmacology and toxicology is the path by which a drug, fluid. Apply onecompartment pharmacokinetics to single and multiple dosing following the intravenous and oral administration of drugs. Some suffer permanent disability and for others the errors are fatal. Same as oral drug can be administered for local effect ensures greater potency because drug directly enters the blood and bypass the liver.
Disadvantages disadvantages of sublingual and buccal. Describe the roles and responsibilities of nurses regarding safe drug administration 2. Learnerdevelop, integrate, and apply knowledge from the foundational sciences pharmaceutical. Chapter 7 pharmacological principles psychopharmacology, one of the most active and developing areas of psychiatric research, is the use of psychotropic medication to treat psychiatric disorders. As in this route the drug does not go to the stomach so it is not destroyed by the enzymes and acids present in the stomach so that it is stable. Introduction to pharmacokinetics and pharmacodynamics. The legal and professional consequences of administering drugs via enteral feeding tubes 38 8. On an increase in the pharmacodynamics of bound drugs c.
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